Azelaic Acid

Azelaic acid is an organic compound found in wheat, rye, and barley. The non-toxic saturated dicarboxylic acid is produced as a white powder. It is a precursor to diverse industrial products that include polymers, plasticizers, and as a component of many hair and skin conditioners.


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Azelaic acid is an organic compound with the chemical formula C9H16O4 and CAS Number 123-99-9.

Esters of dicarboxylic acid are used in lubrication and plasticizers. With hexamethylenediamine, azelaic acid forms Nylon-6,9, which is a specialized plastic.

Azelaic acid is produced industrially by the ozonolysis of oleic acid. The by- product is nonanoic acid. It is produced naturally by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. The bacterial degradation of nonanoic acid produces azelaic acid.

  • Azelaic acid is soluble in hot water, alcohol and organic solvents.
  • Azelaic acid is used in the manufacture of adhesives and sealant chemicals; lubricants and lubricant additives; paint and coating additives, and plasticizers.
  • Medically, Azelaic acid is used to treat mild to moderate acne, both comedonal acne and inflammatory acne.

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